Review of Xailin Night alternatives

7 Best Xailin Night alternative eye ointments

Xailin Night eye ointment has been out of stock for a while now. Xailin Night is a popular option for the management of dry eyes at night time. Xailin Night alternative ointments and eye drops have been in demand. What Xailin Night alternative lubricating products are currently available?

What is Xailin Night?

Xailin Night is a multi-dose, preservative-free eye ointment for the management of dry eyes at night and other eye problems, for example, corneal abrasions.

Dry eyes, also known as dry eye syndrome is a condition where your eyes do not produce enough tears or the tears produced are of poor quality. Tears are essential for maintaining the health of the front surface of your eyes and for providing clear vision. They help keep the eyes lubricated, nourished, and protected against infections.

Dry Eye symptoms

Dry eye symptoms and management with eye ointments and eye drops

When you have dry eyes, you might experience symptoms such as:

  • Stinging or burning sensation: Your eyes might feel like they’re burning or stinging.
  • Redness: The eyes can appear red or bloodshot due to irritation.
  • Gritty or scratchy sensation: You might feel as if there’s sand or grit in your eyes.
  • Blurry vision: Vision might become temporarily blurred, especially when reading or using screens for an extended period.
  • Sensitivity to light: Bright lights might become uncomfortable.
  • Watery eyes: Paradoxically, dry eyes can sometimes lead to excessive tearing as the eyes try to compensate for the lack of proper lubrication.

Some symptoms of dry eyes resemble symptoms of conjunctivitis, an acute eye condition, which can be treated with antibiotic eye drops or ointment.

Several factors can contribute to dry eyes, including:

  • Ageing: Tear production tends to decrease with age.
  • Environmental factors: Dry or windy environments, air conditioning, and heating can contribute to dry eyes.
  • Computer use: Prolonged screen time can reduce blinking and lead to dryness.
  • Contact lenses: Contact lenses can exacerbate dry eye symptoms.
  • Medical conditions: Conditions like autoimmune diseases, diabetes, and thyroid disorders can contribute to dry eyes.
  • Drugs: Some medications, such as antihistamines, decongestants, and certain antidepressants, can cause or worsen dry eyes.
  • Eyelid problems: Conditions that prevent proper blinking or close properly, like blepharitis or eyelid deformities, can lead to dry eyes.
  • Hormonal changes: Hormonal changes, particularly in women during pregnancy or menopause, can affect tear production

Why Xailin Night is a popular ointment for the management of dry eyes at night?

Xailin Night and other eye ointments are used for dry eyes at night because they provide longer-lasting lubrication and protection to the eyes while you sleep. Unlike artificial tears, which are typically watery and provide temporary relief, eye ointments have a thicker and more viscous consistency. This thicker texture allows the ointment to adhere to the surface of the eye and provide extended moisturization throughout the night.

Using Xailin Night at night offers a few advantages in the management of dry eyes:

Prolonged lubrication: Ointments have a more sustained lubricating effect compared to watery eye drops. They can help prevent the eyes from becoming dry and irritated during the night when you might experience reduced blinking and tear production.

Minimal blinking: When you sleep, your blink rate decreases significantly. This reduced blinking can contribute to dryness and discomfort. Eye ointments provide a protective layer over the eyes, helping to minimize the impact of decreased blinking.

Longer lasting: Due to their thicker consistency, eye ointments tend to stay in contact with the eye’s surface for a longer time. This can be particularly beneficial during an extended period of sleep.

Reduced evaporation: The thicker texture of eye ointments can help reduce the evaporation of tears from the eye’s surface. This is important because tear evaporation is a common issue in individuals with dry eyes.

Eye protection: Eye ointments can help protect the surface of the eye from exposure to irritants, allergens, and environmental factors that could exacerbate dry eye symptoms.

Can you buy Xailin Night over the counter?

Xailin Night can be purchased over the counter without a prescription.

Xailin Night ingredients

In order to identify Xailin Night alternatives, firstly we need to look at Xailin Night ingredients.

Active ingredients found in Xailin Night eye ointment:

  • White soft paraffin 57.3%
  • White mineral oil 42.5%
  • Lanolin alcohols 0.2%

The above ingredients produce a transparent and lubricating film on the surface of the eye, which retains moisture in the eye.  

Best Xailin Night alternative products  

Unfortunately, no other brand of eye ointment contains the same active ingredients which are found in Xailin Night eye ointment. Some Xailin Night alternatives have a composition of one active ingredient found in Xailin Night usually in combination with other active ingredients.

1. Xailin Night alternative: Hylo Night eye ointment

Xailin Night alternative Hylo Night eye ointment

Hylo Night eye ointment has the same use as Xailin Night. Hylo Night provides prolonged, night-time relief from dry eye symptoms. Hylo Night comes also as a preservative-free formulation. Hylo Night was previously known as Vita-Pos eye ointment.

Hylo Night: active ingredients  

The main active ingredients found in Hylo Night are:  

  • Vitamin A
  • liquid paraffin
  • light liquid paraffin
  • wool fat
  • white soft vaseline

Hylo Night contains Vitamin A, which is a natural component of the tear, which improves the suitability of the ointment and good mixability with tears.

Despite having a different composition, Hylo Night eye ointment should be considered a good Xailin Night alternative.

What is the availability of Hylo Night eye ointment?

During the Xailin Night shortage, the availability of Hylo Night eye ointment was reduced with reported out of stock status till the end of August.

2. Hycosan Night Eye Ointment

Hycosan Night - Xailin Night eye ointment alternative

Hycosan Night Eye Ointment is another Vitamin A-containing, preservative-free eye ointment formulation.

Hycosan Night Eye Ointment: active ingredients

Active ingredients found in Hycosan Night eye ointment are the same as ingredients found in Hylo Night (except vaseline) making it not only a good Xailin Night alternative, but also Hycosan Night alternative. Hycosan Night contains:

  • Vitamin A
  • liquid paraffin
  • light liquid paraffin
  • wool fat

What is the availability of Hycosan Night eye ointment?

A quick search of two main pharmaceutical wholesalers reveals poor availability at the moment (August 23’). However, a search on the Boots website (local search) shows good availability in stores and online. Hycosan Night eye ointment can also be purchased on Amazon, see the link below.

No products found.

3. HydraMed Night eye ointment

Artelac nightime gel for dry eyes

HydraMed Night eye ointment is a less-known brand of nighttime eye ointment. HydraMed Night ointment is a preservative-free formulation.

HydraMed eye ointment: ingredients

The main ingredients found in HydraMed eye ointment are:

  • Vitamin A
  • chamomile (Matricaria recutita, liposoluble extract)
  • calendula (Calendula o­fficinalis, liposoluble extract)
  • lanoline
  • vaseline oil
  • white vaseline

HydraMed eye ointment has different ingredients from previously discussed eye ointments. The addition of chamomile, calendula (herbal plant) and lanoline, make it stand out from other eye ointment.

Unfortunately at the moment, HydraMed eye ointment is out of stock in main pharmaceutical wholesalers. It can be purchased directly from the Farmigea website.

4. HydraMed Night Sensitive eye ointment

Another eye ointment in the HydraMed range, HydraMed Night Sensitive has better availability online and can be ordered by pharmacies from wholesalers. It seems however that wholesaling prices are much higher than prices for the product online.

No products found.

HydraMed Night Sensitive eye ointment lacks lanolin in its composition, which makes the ointment thicker, providing for ‘enhanced’ comfort.

HydraMed Night Sensitive: active ingredients

HydraMed Night Sensitive has a much simpler composition than HydraMed Night eye ointment. It contains only three ingredients:

  • Vitamin A
  • Liquid paraffin,
  • White soft paraffin

5. Artelac Nighttime Gel

Artelac Nighttime Gel is the first nighttime eye product which has a different formulation from previously discussed eye ointment. There are plenty of eye gels on the market used for the relief of dry eye symptoms. Artelac Nighttime Gel combines three main ingredients:

  • Triglyceride lipids – help seal in moisture
  • Carbomer gel – improves and prolongs adhesion to the surface of the eye
  • Sterile water – replaces the water loss

Unlike other products reviewed, Artelac contains a preservative – cetrimide.

6. Optrex Night Restore eye gel                                         

Optrex is a popular range of eye care products sold in most pharmacies and supermarkets. Like many other eye drop brands, Optrex Night Restore eye gel contains sodium hyaluronate as one of the main active ingredients.

Sodium Hyaluronate is a salt form of hyaluronic acid, which is a substance that is naturally found in the body, particularly in the eyes, joints, and skin. Sodium hyaluronate has several properties that make it beneficial for treating dry eyes. It provides lubrication, promotes water retention, healing and extended relief of symptoms.

Optrex Night Restore is formulated into a gel, which means it is a thicker composition when compared to eye drops. With many eye ointments currently out of stock, Optrex Night Restore gel should be considered as Xailin Night Alternative.

Plenty of other eye drops are sold in pharmacies and online, many of which are advertised as night-time drops, despite having the same active ingredients as daily eye drops/eye gel products.

One popular brand of Sodium Hyaluronate containing eye drops are Hycosan Extra eye drops.

7. Hycosan Extra

No products found.

Although not advertised specifically as a night time eye drops, Hycosan Extra eye drops should be considered by people with severe and persistent dry eyes. A higher concentration of sodium hyaluronate offers effective relief of dry eye symptoms. Hycosan Extra eye drops are preservative-free, contact lens compatible and come in easy to use press-on bottle.


Xailin Night eye ointment has few alternatives, however, the overall availability of nighttime eye ointment for dry eyes is poor at the moment. Hycosan Night time seems to have the best availability out of all Xailin Night alternative ointments.

What is the best nighttime eye ointment for dry eyes?

Several eye ointments can be used for the management of dry eye symptoms. Each nightime eye ointment have different active ingredients. One should expect to try one or more nightime eye ointments to see which ointment is the best to control their symptoms.

What can I use instead of lubricating eye drops?

Lubricating eye gels and lubricating eye ointments should be considered instead or alongside eye drops for the management of dry eyes. Lubricating eye gels and ointments are long-lasting and may provide a better relief from the symptoms.

Can you buy Xailin over the counter?

Xailin gel and Xailin Night eye ointment can both be purchased over the counter.

What does Xailin night contain?

Xailin Night contains a combination of white soft paraffin, white mineral oil, and lanolin alcohols.

How can I hydrate my eyes at night?

Nightime eye gels and ointment are used to hydrate eyes at night. Eye gels and eye ointments provide prolonged lubrication of dry eyes at night.

I am a qualified pharmacist working in an independent pharmacy in the UK.
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